Skeletal Muscle Rhabdomyosarcomas in Inbred Laboratory Mice
نویسندگان
چکیده
منابع مشابه
Muscle-specific gene expression in rhabdomyosarcomas and stages of human fetal skeletal muscle development.
Rhabdomyosarcomas (RMS) bear a morphological resemblance to developing striated muscle. It has been reported that two histologically distinct subtypes of RMS, embryonal and alveolar, behave differently in many clinical aspects, such as age distribution, primary site, and prognosis. We have investigated the expression of various genes, which are preferentially expressed in normal muscle tissue o...
متن کاملStages of Human Fetal Skeletal Muscle Development Muscle-specific Gene Expression in Rhabdomyosarcomas and Updated Version
Rhabdomyosarcomas (RMS) bear a morphological resemblance to developing striated muscle. It has been reported that two histologically distinct subtypes of RMS, embryonal and alveolar, behave differently in many clinical aspects, such as age distribution, primary site, and prog nosis. We have investigated the expression of various genes, which are preferentially expressed in normal muscle tissue ...
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Introduction: Ursolic Acid (UA) is a lipophilic triterpenoid compound, found in large amounts in apple peel. Anabolic effects of UA on the skeletal muscle and the role of this tissue as a key regulator of systematic aging aroused this question in mind whether UA might amend skeletal muscle performances such as myoglobin expression and also whether it switches skeletal muscle fibers from glyc...
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Rhabdomyosarcomas (RSCs) are skeletal muscle neoplasms found in humans and domestic mammals. The A/J inbred strain developed a high frequency (between 70-80%) of adult pleomorphic type (APT) RSC at >20 months of age while BALB/cByJ also develop RSC but less frequently. These neoplasms invaded skeletal muscle surrounding either the axial or proximal appendicular skeleton and were characterized b...
متن کاملDelta-Like 1 Homolog (Dlk1): A Marker for Rhabdomyosarcomas Implicated in Skeletal Muscle Regeneration
Dlk1, a member of the Epidermal Growth Factor family, is expressed in multiple tissues during development, and has been detected in carcinomas and neuroendocrine tumors. Dlk1 is paternally expressed and belongs to a group of imprinted genes associated with rhabdomyosarcomas but not with other primitive childhood tumors to date. Here, we investigate the possible roles of Dlk1 in skeletal muscle ...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 1991
ISSN: 0300-9858,1544-2217
DOI: 10.1177/030098589102800303